Feruloyltyramine( —— )

Catalog No. M18968 CAS No. 66648-43-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Feruloyltyramine
Note

Research use only, not for human use.
Brief Description

NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor.
Description

N-trans-Feruloyltyramine(NTF) has hepatoprotective effect. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor. NTF inhibits melanogenesis in a dose-dependent manner, NTF induces downregulation of tyrosinase resulted in suppression of melanin biosynthesis in murine B16 melanoma cells.
In Vitro

Cell Viability Assay Cell Line:SK-N-SH cells Concentration:10, 25, 50, 100, 150, 250, 500 μM Incubation Time:For 3 hours prior H2O2Result:Protected the cells against H2O2 (150 μM)-induced toxicity as determined by a significant higher percentage of viability in cells.Western Blot Analysis Cell Line:SK-N-SH cells Concentration:25, 50, 100 μM Incubation Time:For 3 hours prior H2O2 Result:Abolished H2O2-induced Bax expression. Significantly decreased activated caspase-3 levels.
In Vivo

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Synonyms

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Pathway

Microbiology/Virology
Target

HIV
Recptor

Others
Research Area

Others-Field
Indication

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