Ursonic Acid( 3-Ketoursolic acid )

Catalog No. M18918 CAS No. 6246-46-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Ursonic Acid
Note

Research use only, not for human use.
Brief Description

Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
Description

Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
In Vitro

Cell Proliferation Assay Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited cell proliferation in a dose-dependent manner.Western Blot Analysis Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited the anti-apoptotic signaling (pAkt1, pIκBα, NF-κBp65 and Bcl-2).
In Vivo

Animal Model:Adult male albino ratsDosage:5-20 mg/kg Administration:p.o., twice a day, 30 days Result:Increased weight gain and food intake.Decreased AST and ALT activities and total and indirect bilirubin levels.Increased direct bilirubin and levels of non-enzymic antioxidants (GSH, ascorbic acid and a-tocopherol).Decreased lipid peroxidation.
Synonyms

3-Ketoursolic acid
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

6246-46-4
Formula Weight

454.69
Molecular Formula

C30H46O3
Purity

>98% (HPLC)
Solubility

DMSO : 10 mg/mL 21.99 mM;
SMILES

[C@H]1(CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]3[C@@]4(CCC(=O)C3(C)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O)C
Chemical Name

——

1. Yanuar A, et al. Bioinformation. 2014 Feb 19;10(2):52-5.

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