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n-Butylidenephthalide

CAS No. 551-08-6

n-Butylidenephthalide( Butylidenephthalide | BP | 3-Butylidene Phthalide )

Catalog No. M18790 CAS No. 551-08-6

(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	35	In Stock
5MG	29	In Stock
10MG	46	In Stock
25MG	72	In Stock
50MG	100	In Stock
100MG	145	In Stock
200MG	212	In Stock
500MG	362	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

n-Butylidenephthalide
Note

Research use only, not for human use.
Brief Description

(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
Description

Butylidenephthalide is an inhibitor of platelet-derived growth factor (PDGF). Butylidenephthalide activity leads to the reduction of liver fibrosis, increased Nur77 (NR4A1) expression, and downregulation of EMT-related genes such as Snail (Snail/SNAI1) and Slug (Slug/SNAI2).
In Vitro

3-Butylidenephthalide (Butylidenephthalide) abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis.
In Vivo

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Synonyms

Butylidenephthalide | BP | 3-Butylidene Phthalide
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

α-glucosidase
Research Area

——
Indication

——

Chemical Information

CAS Number

551-08-6
Formula Weight

188.22
Molecular Formula

C12H12O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (1328.23 mM)
SMILES

CCCC=C1C2=CC=CC=C2C(=O)O1
Chemical Name

3-Butylidene-2-benzofuran-1-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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