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S-(5'-Adenosyl)-L-methionine tosylate
S-(5'-Adenosyl)-L-methionine tosylate
CAS No. 52248-03-0
S-(5'-Adenosyl)-L-methionine tosylate( —— )
Catalog No. M18717 CAS No. 52248-03-0
S-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 27 | Get Quote |
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| 25MG | 41 | Get Quote |
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| 50MG | 60 | Get Quote |
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| 100MG | 78 | Get Quote |
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| 200MG | 123 | Get Quote |
|
| 500MG | 249 | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameS-(5'-Adenosyl)-L-methionine tosylate
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NoteResearch use only, not for human use.
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Brief DescriptionS-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.
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DescriptionS-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases. SAM (tosylate) (SAMe) is a stable salt of SAM that is included in nutritional supplements for oral use. SAMe reportedly ameliorates depression, pain associated with osteoarthritis and fibromyalgia, and liver toxicity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetChloride Channel
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number52248-03-0
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Formula Weight570.64
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Molecular FormulaC22H30N6O8S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 150 mg/mL (262.86 mM)
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SMILESCc1ccc(cc1)S([O-])(=O)=O.C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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D-Alanine
Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist with an EC50 of 9 mM for GlyR.
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Eact
Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
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GaTx2
Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.2.
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