Auraptene( 7-Geranyloxycoumarin, Aurapten, Auraptene )

Catalog No. M18649 CAS No. 495-02-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Auraptene
Note

Research use only, not for human use.
Brief Description

Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7.
Description

Aurapten is a coumarin with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis. Aurapten may also be useful in the treatment of Alzheimer’s disease by inhibiting β-secretase (BACE1) activity.
In Vitro

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In Vivo

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Synonyms

7-Geranyloxycoumarin, Aurapten, Auraptene
Pathway

Others
Target

Other Targets
Recptor

BACE1
Research Area

Cancer|Inflammation/Immunology
Indication

——

CAS Number

495-02-3
Formula Weight

298.4
Molecular Formula

C19H22O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (167.57 mM)
SMILES

CC(=CCC/C(=C/COc1cc2c(cc1)ccc(=O)o2)/C)C
Chemical Name

2H-1-Benzopyran-2-one, 7-((3,7-dimethyl-2,6-octadienyl)oxy)-, (E)-

1.Murakami, A.,Nakamura, Y.,Tanaka, T., et al. Carcinogenesis 21(10), 1843-1850 (2000).

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