2-Deoxy-D-galactose
CAS No. 1949-89-9
2-Deoxy-D-galactose( —— )
Catalog No. M37322 CAS No. 1949-89-9
2-Deoxy-D-galactose is a glucose analog and glucose antagonist that inhibits the maintenance of hippocampal LTP and can suppress tumor growth by inhibiting the glycolytic process.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
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| 200MG | Get Quote | In Stock |
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| 500MG | 73 | In Stock |
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| 1G | 108 | In Stock |
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Biological Information
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Product Name2-Deoxy-D-galactose
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NoteResearch use only, not for human use.
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Brief Description2-Deoxy-D-galactose is a glucose analog and glucose antagonist that inhibits the maintenance of hippocampal LTP and can suppress tumor growth by inhibiting the glycolytic process.
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Description2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo.
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In Vitro2-Deoxy-D-galactose (1 mM/L; 5 h) is rapid phosphorylation during the first 30 min and decreases to approximately 20% of this rate during the subsequent hours in ascites hepatoma cells.
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In Vivo2-Deoxy-D-galactose (380 mg/kg; i.p.; for 6 times) strongly decreases contents of UMP, UDPG, and UDP galactose in rat livers.2-Deoxy-D-galactose (2-8 μM; intracerebroventricularly injection; once) shows PAR impairment 30 min before the acquisition trial a dose of 4 μM and 15 min delay after do-gal administration.Animal Model:Male adult Wistar rats with passive avoidance response (PAR) acquisition trial Dosage:2, 4 and 8 μM Administration:Intracerebroventricularly injection; 2-8 μM; once Result:Exhibited PAR disruption at a dose of 4 μM.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1949-89-9
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Formula Weight164.16
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Molecular FormulaC6H12O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 250 mg/mL (1522.90 mM; Ultrasonic) Methanol : 125 mg/mL (761.45 mM; Ultrasonic)
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SMILESOC[C@@H](O)[C@H](O)[C@H](O)CC=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Keppler DO, et al. The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis. Eur J Biochem. 1970 Dec;17(2):246-53.?
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