Saccharin 1-methylimidazole (SMI)

CAS No. 482333-74-4

Saccharin 1-methylimidazole (SMI)( Saccharin 1-methylimidazole )

Catalog No. M18618 CAS No. 482333-74-4

SMI is a general-purpose activator used for DNA and RNA synthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 32 In Stock
50MG 47 In Stock
100MG 77 In Stock
200MG 101 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Saccharin 1-methylimidazole (SMI)
  • Note
    Research use only, not for human use.
  • Brief Description
    SMI is a general-purpose activator used for DNA and RNA synthesis.
  • Description
    Saccharin 1-methylimidazole is an activator for DNA and RNA synthesis.
  • In Vitro
    Exposure to certain concentrations of the entirely different promoters phenobarbital and the calcium and sodium salts of saccharin (22, 23, 25, 29, 38) stimulates calcium-deprived T51B cells to initiate DNA synthesis as rapidly and as effectively, or nearly as effectively, as raising the extracellular calcium concentration to 1.25 mM.
  • In Vivo
    ——
  • Synonyms
    Saccharin 1-methylimidazole
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    482333-74-4
  • Formula Weight
    265.29
  • Molecular Formula
    C7H5NO3S·C4H6N2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 6 mg/mL 22.62 mM
  • SMILES
    O=C1c2c(cccc2)S(=O)(=O)N1.Cn1ccnc1
  • Chemical Name
    1,1-Dioxide-1,2-benzisothiazol-3(2H)-one 1-methyl-1H-imidazole salt

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Boynton AL, et al. Cancer Res. 1980 Dec;40(12):4541-5.
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