20(R)-Propanaxadiol

CAS No. 38243-03-7

20(R)-Propanaxadiol( —— )

Catalog No. M18496 CAS No. 38243-03-7

20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 33 In Stock
10MG 40 In Stock
25MG 67 In Stock
50MG 91 In Stock
100MG 136 In Stock
200MG 198 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    20(R)-Propanaxadiol
  • Note
    Research use only, not for human use.
  • Brief Description
    20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.
  • Description
    R-Ginsenodie Rg3 γ2 GABA-A receptor agonist, 7.1 K+ channel activator, α10 nAChR antagonist found in Panax. It exhibits a wide variety of biological activities, including decreasing expression of pro-inflammatory cytokines, reducing oxidative stress, and inhibiting tubular formation and migration of endothelial progenitor cells.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Kunming mice weighing 18-22 g Dosage:0.05 mg/kg, 0.1 mg/kg, 0.5 mg/kg (5 μL each nostril) Administration:Intranasal administration; for 2 weeks Result:Significantly prolonged the weight-loaded swimming time, and also increased the hepatic glycogen levels.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    38243-03-7
  • Formula Weight
    785.02
  • Molecular Formula
    C42H72O13
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 41.67 mg/mL (53.08 mM)
  • SMILES
    C1[C@@H](C([C@H]2[C@](C1)([C@@H]1[C@@](CC2)([C@]2([C@H]([C@@H](C1)O)[C@H](CC2)[C@@](C)(CCC=C(C)C)O)C)C)C)(C)C)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)O)CO
  • Chemical Name
    (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((3R,5S,8R,9R,10R,12S,13R,14R,17S)-12-hydroxy-17-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bae EA,et al. Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities. Biol Pharm Bull. 2002 Jan;25(1):58-63.
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