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Fraxinellone
CAS No. 28808-62-0
Fraxinellone( Fraxinellone )
Catalog No. M18367 CAS No. 28808-62-0
Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 74 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 155 | In Stock |
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| 50MG | 230 | In Stock |
|
| 100MG | 346 | In Stock |
|
| 200MG | 510 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFraxinellone
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NoteResearch use only, not for human use.
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Brief DescriptionFraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease.
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DescriptionFraxinellone has anti-inflammatory properties. Fraxinellone was found to inhibit LPS-induced nitric oxide (NO) and prostaglandin E(2) (PGE(2)) production, and to reduce the LPS-induced expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) at the mRNA and protein levels in a dose-dependent manner.
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In VitroCell Viability Assay Cell Line:A549 cells Concentration:0 μM, 10 μM, 30 μM, 100 μM Incubation Time:12 hours Result:Inhibited the percent of PD-L1 positive cells.
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In VivoAnimal Model:BALB/c nude miceDosage:30 and 100?mg/kg Administration:Oral gavage; 30 and 100?mg/kg; every three days; 30 daysResult:Significantly suppressed tumor growth.
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SynonymsFraxinellone
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number28808-62-0
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Formula Weight232.27
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Molecular FormulaC14H16O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (430.51 mM)
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SMILESCC1=C2C(=O)OC(C2(CCC1)C)C3=COC=C3
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Chemical Name1(3H)-Isobenzofuranone, 3-(3-furanyl)-3a,4,5,6-tetrahydro-3a,7-dimethyl-, (3R-cis)- (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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