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Allopurinol Sodium
CAS No. 17795-21-0
Allopurinol Sodium( —— )
Catalog No. M18135 CAS No. 17795-21-0
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 37 | In Stock |
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| 25MG | 85 | In Stock |
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| 50MG | 119 | In Stock |
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| 100MG | 179 | In Stock |
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| 200MG | 266 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAllopurinol Sodium
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NoteResearch use only, not for human use.
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Brief DescriptionAllopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
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DescriptionAllopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
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In VitroAllopurinol sodium (0, 10, 100, 1000 μg/ml; 17 h) decreases the expression of HIF-1α and HIF-2α protein in HFF and HUVEC cells.Allopurinol sodium (0, 10, 100, 1000 μg/ml; 24 h) reduces angiogenesis traits of HUVEC cells. Western Blot Analysis Cell Line:HFF, HUVEC cells Concentration:0, 10, 100, 1000 μg/ml Incubation Time:17 h Result:Reduced HIF-1α and HIF-2α protein expression in a dose dependent manner.
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In VivoAllopurinol sodium (39 mg/kg; p.o.; daily for 21 successive days) shows anti-depressant activity in mouse.Allopurinol sodium (10-400 mg/kg; i.p.) induces anti-nociception activity in mouse. Animal Model:20-30 g, male Swiss Albino mice Dosage:39 mg/kg Administration:P.o.; daily for 21 successive days Result:Reduced the immobility time in the FST with the immobility time of 129.8±10.5 s.Animal Model:30-40 g, male adult Swiss albino mice Dosage:10, 50, 100, 200, 400 mg/kg Administration:I.p.Result:Produced dose-dependent anti-nociception in the tail-flick, hot-plate.
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorXO
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number17795-21-0
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Formula Weight159.1
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Molecular FormulaC5H4N4NaO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 50 mg/mL (314.27 mM)
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SMILES[Na+].O=C1NC=NC2=C1C=NN2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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