Picolinamide

CAS No. 1452-77-3

Picolinamide( —— )

Catalog No. M18028 CAS No. 1452-77-3

Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 27 In Stock
50MG 38 In Stock
100MG 52 In Stock
200MG 86 In Stock
500MG 163 In Stock
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Biological Information

  • Product Name
    Picolinamide
  • Note
    Research use only, not for human use.
  • Brief Description
    Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
  • Description
    Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
  • In Vitro
    Picolinamide (10 μM-1 mM) inhibits Poly(ADP-ribose) synthetase activity.Picolinamide (2 mM) protects against streptozotocin-induced depression of proinsulin synthesis in isolated pancreatic islets of rats.
  • In Vivo
    Picolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles.Picolinamide (250 mg/kg, i.p., rats) enhances the tumorigenic effect of Streptozotocin and Alloxan on islet B-cells. Animal Model:Rats Dosage:4 mmol/kg Administration:Intraperitoneal injection (i.p.)Result:Increased renal cortical NAD content (1.5 fold).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PARP
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1452-77-3
  • Formula Weight
    122.12
  • Molecular Formula
    C6H6N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (818.87 mM)
  • SMILES
    C1=CC=NC(=C1)C(=O)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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