Dyngo-4a

CAS No. 1256493-34-1

Dyngo-4a( Dyngo-49 | Dyngo 49 | Hydroxy Dynasore )

Catalog No. M17909 CAS No. 1256493-34-1

Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 41 In Stock
10MG 68 In Stock
25MG 125 In Stock
50MG 210 In Stock
100MG 312 In Stock
200MG 464 In Stock
500MG 743 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dyngo-4a
  • Note
    Research use only, not for human use.
  • Brief Description
    Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.
  • Description
    Dyngo-49 is a dynamin inhibitor.
  • In Vitro
    ——
  • In Vivo
    Animal Model:CD-1 mice.Dosage:30 mg/kg Administration:Intraperitoneal injection; 1.5–2 h before BoNT/A injection Result:Protected BoNT/A-induced paralysis in vivo.
  • Synonyms
    Dyngo-49 | Dyngo 49 | Hydroxy Dynasore
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DynI (brain)| DynI (rec)| DynII (rec)
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1256493-34-1
  • Formula Weight
    338.31
  • Molecular Formula
    C18H14N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (147.79 mM)
  • SMILES
    c1c(c(cc2ccccc12)O)C(=O)NN=Cc1c(cc(c(c1)O)O)O
  • Chemical Name
    3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Harper CB., Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors. Trends Cell Biol. 2013 Feb;23(2):90-101.
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