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Ochromycinone

CAS No. 111540-00-2

Ochromycinone( STA21 | Ochromycinone | NSC 628869 )

Catalog No. M17821 CAS No. 111540-00-2

STA-21 is a selective STAT3 inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	145	In Stock
5MG	132	In Stock
10MG	227	In Stock
25MG	468	In Stock
50MG	807	In Stock
100MG	1088	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Ochromycinone
Note

Research use only, not for human use.
Brief Description

STA-21 is a selective STAT3 inhibitor.
Description

STA-21 is a promising STAT-3 inhibitor that reciprocally regulates Th17 and Treg cells, inhibits osteoclastogenesis in mice and humans and alleviates autoimmune inflammation in an experimental model of rheumatoid arthritis. STA-21 improved the clinical course of arthritis in IL-1Ra-KO mice. It increased not only the number of Treg cells but also the function of the Treg cells. It also suppressed Th17 cells and osteoclast formation. These data suggest that STA-21 might be an effective treatment for patients with RA.
In Vitro

——
In Vivo

——
Synonyms

STA21 | Ochromycinone | NSC 628869
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

STAT3
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

111540-00-2
Formula Weight

306.31
Molecular Formula

C19H14O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 16.67 mg/mL (54.42 mM)
SMILES

CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O
Chemical Name

8-hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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