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BMS-833923
CAS No. 1059734-66-5
BMS-833923( XL-139 )
Catalog No. M17789 CAS No. 1059734-66-5
BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
|
| 5MG | 44 | In Stock |
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| 10MG | 70 | In Stock |
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| 25MG | 123 | In Stock |
|
| 50MG | 193 | In Stock |
|
| 100MG | 350 | In Stock |
|
| 200MG | 514 | In Stock |
|
| 500MG | 817 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBMS-833923
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
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DescriptionBMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
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In Vitro——
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In Vivo——
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SynonymsXL-139
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PathwayApoptosis
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TargetIL Receptor
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RecptorSmoothened
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1059734-66-5
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Formula Weight473.57
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Molecular FormulaC30H27N5O
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Purity>98% (HPLC)
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SolubilityDMSO : 50 mg/mL 105.58 mM;
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SMILESc12c(c(nc(n1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1C)CNC)c1ccccc1)cccc2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tang JY, et al. Semin Cutan Med Surg. 2011, 30(4 Suppl), S14-18.2. Zaidi AH, et al. Y Invest. 2013, 31(7), 480-489.
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