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Ascomycin
CAS No. 104987-12-4
Ascomycin( FK-520 | FR900520 | L-683590 | Changchuanmycin )
Catalog No. M17780 CAS No. 104987-12-4
Ascomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
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| 5MG | 34 | In Stock |
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| 10MG | 49 | In Stock |
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| 50MG | 59 | In Stock |
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| 100MG | 75 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAscomycin
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NoteResearch use only, not for human use.
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Brief DescriptionAscomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
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DescriptionAscomycin, also known as KF-520, FR900520, L 683590, produced by the fermentation of S. hygroscopicus subsp. ascomyceticus, is an ethyl analog of tacrolimus (FK-506) with potent immunosuppressant properties.
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In Vitro——
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In Vivo——
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SynonymsFK-520 | FR900520 | L-683590 | Changchuanmycin
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PathwayOthers
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TargetOther Targets
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Recptorcalcineurin phosphatase
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number104987-12-4
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Formula Weight792.01
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Molecular FormulaC43H69NO12
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 39 mg/mL; 49.24 mM
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SMILESO1[C@@]2(O)C(=O)C(=O)N3[C@H](C(=O)O[C@@H]([C@@H]([C@@H](O)CC(=O)[C@@H](/C=C(/C[C@@H](C[C@H](OC)[C@@H]1[C@@H](OC)C[C@H]2C)C)\C)CC)C)/C(=C/[C@H]1C[C@@H](OC)[C@H](O)CC1)/C)CCCC3
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Chemical Name(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hatanaka H, et al. J Antibiot (Tokyo). 1988, 41(11), 1592-1601.
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