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RP-54745
CAS No. 135330-08-4
RP-54745( —— )
Catalog No. M20324 CAS No. 135330-08-4
RP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 145 | In Stock |
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| 5MG | 155 | In Stock |
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| 10MG | 250 | In Stock |
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| 25MG | 455 | In Stock |
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| 50MG | 631 | In Stock |
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| 100MG | 886 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRP-54745
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NoteResearch use only, not for human use.
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Brief DescriptionRP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
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DescriptionRP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
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In VitroRP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
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In VivoRP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorinterleukin-1
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Research Area——
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Indication——
Chemical Information
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CAS Number135330-08-4
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Formula Weight297.8
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Molecular FormulaC13H12ClNOS2?
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL?(209.86 mM)
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SMILESCC1N(CCc2ccccc12)c1ssc(=O)c1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Moth Cytochrome C (M...
Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.This peptide is derived from the carboxyl terminus of moth cytochrome c. Thymic positive and negative selections govern the development of a self-MHC-reactive, yet self-tolerant, T cell repertoire.
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Ethyl oleate
Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs).?NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration.?
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Fibrinopeptide A, hu...
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively.
