Cart
sales@molnova.com
Home - Products - Others - Other Targets - RP-54745

RP-54745

CAS No. 135330-08-4

RP-54745( —— )

Catalog No. M20324 CAS No. 135330-08-4

RP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 145 In Stock
5MG 155 In Stock
10MG 250 In Stock
25MG 455 In Stock
50MG 631 In Stock
100MG 886 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    RP-54745
  • Note
    Research use only, not for human use.
  • Brief Description
    RP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
  • Description
    RP-54745 a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
  • In Vitro
    RP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
  • In Vivo
    RP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    interleukin-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    135330-08-4
  • Formula Weight
    297.8
  • Molecular Formula
    C13H12ClNOS2?
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL?(209.86 mM)
  • SMILES
    CC1N(CCc2ccccc12)c1ssc(=O)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Folliard F Bousseau A Terlain B . RP 54745 a potential antirheumatic compound. I. Inhibitor of macrophage stimulation and interleukin-1 production[J]. Agents and Actions 1992 36(1-2):119-126.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 5-(2-Furyl)-2-hydrox...

    5-(2-Furyl)-2-hydroxybenzoic acid is an inhibitor of glycolate oxidase (GO) and can be used to study metabolism-related disorders such as primary hyperoxaluria type 1 (PH1).

  • Paeonoside

    Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation.

  • EGFR-derived peptide

    EGFR-derived peptide

Sign In Join Free