Gefapixant citrate is an orally active P2X3 receptor (P2X3R) antagonist that acts on human homologous recombinant hP2X3 (IC50: ~30 nM) and hP2X2/3 (IC50: 100-200 nM).

12-Distearoyl-sn-glycero-3-phosphorylethanolamine is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats coco butter and sesame oil. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells as well as being involved in metabolism and signaling.

ortho-Hydroxyphenylacetic acid (2-hydroxybenzeneacetic acid) can be found in a number of food items such as natal plum lemon verbena half-highbush blueberry and parsley which makes ortho-hydroxyphenylacetic acid a potential biomarker for the consumption of these food products. ortho-Hydroxyphenylacetic acid can be found primarily in blood feces and urine.