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alpha-Tocopherolquinone
CAS No. 7559-04-8
alpha-Tocopherolquinone( A-0001 | EPI-A-0001 | Vitamin E Quinone (D-form) )
Catalog No. M17740 CAS No. 7559-04-8
During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 27 | In Stock |
|
| 25MG | 58 | In Stock |
|
| 50MG | 84 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Namealpha-Tocopherolquinone
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NoteResearch use only, not for human use.
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Brief DescriptionDuring hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria.
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Descriptionɑ-Tocopherolquinone, also known as Vitamin E Quinone (D-form), is a mitochondrial membrane transport protein that has been in phase II clinical trials for the treatment of inherited mitochondrial respiratory chain diseases, however this research has been discontinued. It has also been used for the treatment of Frederich's ataxia and MEILAS syndrome.
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In Vitro——
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In Vivo——
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SynonymsA-0001 | EPI-A-0001 | Vitamin E Quinone (D-form)
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number7559-04-8
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Formula Weight446.71
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Molecular FormulaC29H50O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (111.93 mM)
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SMILESCC1=C(C(=O)C(=C(C1=O)C)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O)C
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Chemical Nameɑ-2-(3-Hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-p-benzoquinone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Siegel D, et al. The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant[J]. Molecular Pharmacology, 1997, 52(2):300-305.
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