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BMS202 hydrochloride
CAS No. ——
BMS202 hydrochloride ( —— )
Catalog No. M17711 CAS No. ——
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 101 | Get Quote |
|
| 10MG | 161 | Get Quote |
|
| 25MG | 317 | Get Quote |
|
| 50MG | 566 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBMS202 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM).
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DescriptionPD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetHIF/HIF Prolyl-hydroxylase
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RecptorPD-1/PD-L1
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight455.97
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Molecular FormulaC25H30ClN3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.COc1nc(ccc1CNCCNC(C)=O)OCc3cccc(c2ccccc2)c3C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zak KM, Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).Oncotarget. 2016 May 24;7(21):30323-35.
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