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FPH2

CAS No. 957485-64-2

FPH2( BRD-9424 )

Catalog No. M17692 CAS No. 957485-64-2

FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 41 In Stock
5MG 37 In Stock
10MG 72 In Stock
25MG 180 In Stock
50MG 305 In Stock
100MG 538 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FPH2
  • Note
    Research use only, not for human use.
  • Brief Description
    FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
  • Description
    FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
  • In Vitro
    FPH2 induces functional proliferation of hepatocytes in vitro, and thus may be useful for expanding mature human primary hepatocytes. FPH1 and FPH2 can increase in hepatocyte nuclei count and/or elevate the number of nuclei undergoing mitosis during primary screening, and these effects on hepatocytes are concentration dependent. Cells treated with FPH1 and FPH2 also maintain their liver-specific functions. Over 7 days, FPH2 induces hepatocyte doublings at a rate that is consistent with reported liver regeneration kinetics in vivo.
  • In Vivo
    ——
  • Synonyms
    BRD-9424
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    957485-64-2
  • Formula Weight
    353.83
  • Molecular Formula
    C14H16ClN5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 125 mg/mL; 353.28 mM
  • SMILES
    Clc1cc(NC(=S)Nc2cn(nc2C(=O)N)CC)c(OC)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shan J, et al. Nat Chem Biol. 2013, 9(8), 514-520.
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