Cart
sales@molnova.com
TG100713
CAS No. 925705-73-3
TG100713( TG100713 )
Catalog No. M17665 CAS No. 925705-73-3
TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 50 | In Stock |
|
| 10MG | 80 | In Stock |
|
| 25MG | 160 | In Stock |
|
| 50MG | 302 | In Stock |
|
| 100MG | 444 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTG100713
-
NoteResearch use only, not for human use.
-
Brief DescriptionTG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
-
DescriptionTG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI3Kδ, γ, α and β isoforms respectively). Inhibits endothelial cell proliferation.
-
In VitroTG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation.
-
In Vivo——
-
SynonymsTG100713
-
PathwayCell Cycle/DNA Damage
-
TargetROCK
-
RecptorPI3Kδ , PI3Kγ , PI3Kα , PI3Kβ
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number925705-73-3
-
Formula Weight254.25
-
Molecular FormulaC12H10N6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 6.41 mg/mL (25.21 mM)
-
SMILESC1=CC(=CC(=C1)O)C2=CN=C3C(=N2)C(=NC(=N3)N)N
-
Chemical Name3-(2,4-diaminopteridin-6-yl)phenol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Doukas J et al. Proc Natl Acad Sci U S A, 2006, 103(52), 19866-19871.
molnova catalog
related products
-
MD 39-AM
Anticytokinin activity was evaluated by 50% of the callus growth on the medium with kinetin but without anti-cytokinin
-
Cintirorgon
Cintirorgon is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells.
-
BDP5290
BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM 50 nM 10 nM and 100 nM for ROCK1 ROCK2 MRCKα and MRCKβ respectively.)
