CFMTI

CAS No. 864864-17-5

CFMTI( CFMTI )

Catalog No. M17627 CAS No. 864864-17-5

CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 151 In Stock
10MG 215 In Stock
25MG 419 In Stock
50MG 615 In Stock
100MG 876 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CFMTI
  • Note
    Research use only, not for human use.
  • Brief Description
    CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
  • Description
    CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CFMTI
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Beta Amyloid
  • Recptor
    mGluR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    864864-17-5
  • Formula Weight
    349.37
  • Molecular Formula
    C19H16FN5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 6.2 mg/mL. 17.75 mM;
  • SMILES
    c1(c(nccc1)F)n1nnc(c1C)c1ccc2c(c1)CN(C2=O)C1CC1
  • Chemical Name
    2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Satow A et al. 2009 Jul;330(1):179-90.
molnova catalog
related products
  • β-Amyloid 1-34

    This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.

  • Methyl tridecanoate

    Methyl tridecanoate inhibits β-amyloid aggregation moderately and inhibits acetylcholinesterase (AChE) weekly.

  • Amyloid beta-peptide...

    Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells. The amino acid sequence of Aβ(25-35) peptide is NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-COOH, where the first Gly represents the amino acid 25 and the last Met represents the amino acid 35 and it is also investigated in gel state for the first time.