Cart
sales@molnova.com
CFMTI
CAS No. 864864-17-5
CFMTI( CFMTI )
Catalog No. M17627 CAS No. 864864-17-5
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 136 | In Stock |
|
| 2MG | 75 | In Stock |
|
| 5MG | 123 | In Stock |
|
| 10MG | 180 | In Stock |
|
| 25MG | 321 | In Stock |
|
| 50MG | 445 | In Stock |
|
| 100MG | 621 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCFMTI
-
NoteResearch use only, not for human use.
-
Brief DescriptionCFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
-
DescriptionCFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5.
-
In Vitro——
-
In Vivo——
-
SynonymsCFMTI
-
PathwayMembrane Transporter/Ion Channel
-
TargetBeta Amyloid
-
RecptormGluR
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number864864-17-5
-
Formula Weight349.37
-
Molecular FormulaC19H16FN5O
-
Purity>98% (HPLC)
-
SolubilityDMSO : 6.2 mg/mL. 17.75 mM;
-
SMILESc1(c(nccc1)F)n1nnc(c1C)c1ccc2c(c1)CN(C2=O)C1CC1
-
Chemical Name2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Satow A et al. 2009 Jul;330(1):179-90.
molnova catalog
related products
-
Scyllo-Inositol
Scyllo-Inositol is one of the inositol stereoisomers rare in the nature and expected as a promising disease-modifying therapeutic agent for Alzheimer's disease.
-
β-Amyloid 1-15
This is a fragment of beta-amyloid peptide. It has amino acids 1 through 15.
-
RAGE antagonist pept...
Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
