CFMTI

CAS No. 864864-17-5

CFMTI( CFMTI )

Catalog No. M17627 CAS No. 864864-17-5

CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 136 In Stock
2MG 75 In Stock
5MG 123 In Stock
10MG 180 In Stock
25MG 321 In Stock
50MG 445 In Stock
100MG 621 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CFMTI
  • Note
    Research use only, not for human use.
  • Brief Description
    CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
  • Description
    CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CFMTI
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Beta Amyloid
  • Recptor
    mGluR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    864864-17-5
  • Formula Weight
    349.37
  • Molecular Formula
    C19H16FN5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 6.2 mg/mL. 17.75 mM;
  • SMILES
    c1(c(nccc1)F)n1nnc(c1C)c1ccc2c(c1)CN(C2=O)C1CC1
  • Chemical Name
    2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Satow A et al. 2009 Jul;330(1):179-90.
molnova catalog
related products
  • β-Amyloid (1-42), ra...

    Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.

  • Lecanemab

    Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated β-amyloid (Abeta) with activity against oligomers, protofibrils, and insoluble protofibrils, and may be useful in the study of Alzheimer's disease (AD)-induced mild cognitive impairment and mild AD dementia.

  • β-amyloid 1-11

    Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients.