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Alogliptin
CAS No. 850649-61-5
Alogliptin( Alogliptin )
Catalog No. M17613 CAS No. 850649-61-5
Alogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 42 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 74 | In Stock |
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| 50MG | 91 | In Stock |
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| 100MG | 128 | In Stock |
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| 200MG | 184 | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAlogliptin
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NoteResearch use only, not for human use.
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Brief DescriptionAlogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.
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DescriptionAlogliptin is a DPP-4 inhibitor used for the treatment of Type 2 diabetes. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
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In Vitro——
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In Vivo——
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SynonymsAlogliptin
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorDPP-4
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number850649-61-5
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Formula Weight339.39
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Molecular FormulaC18H21N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (294.65 mM)
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SMILESCN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=CC=CC=C2C#N)C1=O
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Chemical Name(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Feng J, et al. J Med Chem, 2007, 50(10), 2297-2300.
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