CPI-1189

CAS No. 183619-38-7

CPI-1189( CPI-1189 | REN-1189 | REN-1654 | REN1189 )

Catalog No. M17393 CAS No. 183619-38-7

REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
10MG 36 In Stock
25MG 79 In Stock
50MG 127 In Stock
100MG 211 In Stock
200MG 310 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CPI-1189
  • Note
    Research use only, not for human use.
  • Brief Description
    REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
  • Description
    REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
  • In Vitro
    Cell Viability Assay Cell Line:SH-SY5Y oncentration:10, 30, 100, 300 nM Incubation Time:1 h Result:Alleviated OGDR-induced cytotoxicity in a concentration-dependent manner.Apoptosis Analysis Cell Line:SH-SY5Y Concentration:100 nM Incubation Time:1 h Result:Inhibited OGDR-induced caspase-3/-9 activation and ssDNA accumulation.Attenuated OGDR-induced apoptosis activation.
  • In Vivo
    ——
  • Synonyms
    CPI-1189 | REN-1189 | REN-1654 | REN1189
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    183619-38-7
  • Formula Weight
    234.3
  • Molecular Formula
    C13H18N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (426.82 mM)
  • SMILES
    CC(=O)Nc1ccc(cc1)C(=O)NC(C)(C)C
  • Chemical Name
    4-acetamido-N-(tert-butyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bjugstad KB,et al. Preventive actions of a synthetic antioxidant in a novel animal model of AIDS dementia. Brain Res. 1998 Jun 8;795(1-2):349-57.
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