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SR-4370
CAS No. 1816294-67-3
SR-4370( SR-4370 | SR 4370 | SR4370 )
Catalog No. M17385 CAS No. 1816294-67-3
SR- 4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | In Stock |
|
| 5MG | 102 | In Stock |
|
| 10MG | 177 | In Stock |
|
| 25MG | 332 | In Stock |
|
| 50MG | 500 | In Stock |
|
| 100MG | 705 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSR-4370
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NoteResearch use only, not for human use.
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Brief DescriptionSR- 4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3.
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DescriptionSR- 4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp. SR- 4370 is reported in WO 2015153516.
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In VitroSR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. SR-4370 is cytotoxic to the breast cancer cells (MDA-MB-231), with an IC50 of 12.6 μM.
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In Vivo——
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SynonymsSR-4370 | SR 4370 | SR4370
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorHDAC1| HDAC2| HDAC3
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1816294-67-3
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Formula Weight304.34
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Molecular FormulaC17H18F2N2O
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 150 mg/mL; 492.89 mM
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SMILESFc1c(cccc1F)c2ccc(cc2)C(=O)NNCCCC
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Chemical NameN'-butyl-2',3'-difluoro-[1,1'-biphenyl]-4-carbohydrazide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. D Liao, etal. HDAC Inhibitor Compounds and Methods of Treatment
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