Cart
sales@molnova.com
SR-4370
CAS No. 1816294-67-3
SR-4370( SR-4370 | SR 4370 | SR4370 )
Catalog No. M17385 CAS No. 1816294-67-3
SR- 4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | In Stock |
|
| 5MG | 102 | In Stock |
|
| 10MG | 177 | In Stock |
|
| 25MG | 332 | In Stock |
|
| 50MG | 500 | In Stock |
|
| 100MG | 705 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSR-4370
-
NoteResearch use only, not for human use.
-
Brief DescriptionSR- 4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3.
-
DescriptionSR- 4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp. SR- 4370 is reported in WO 2015153516.
-
In VitroSR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. SR-4370 is cytotoxic to the breast cancer cells (MDA-MB-231), with an IC50 of 12.6 μM.
-
In Vivo——
-
SynonymsSR-4370 | SR 4370 | SR4370
-
PathwayCell Cycle/DNA Damage
-
TargetGPR
-
RecptorHDAC1| HDAC2| HDAC3
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1816294-67-3
-
Formula Weight304.34
-
Molecular FormulaC17H18F2N2O
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 150 mg/mL; 492.89 mM
-
SMILESFc1c(cccc1F)c2ccc(cc2)C(=O)NNCCCC
-
Chemical NameN'-butyl-2',3'-difluoro-[1,1'-biphenyl]-4-carbohydrazide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. D Liao, etal. HDAC Inhibitor Compounds and Methods of Treatment
molnova catalog
related products
-
Questiomycin A
Questiomycin A is an antibiotic produced in crème fraiche with antibacterial and anticancer activities. Questiomycin A suppresses expression of GRP78, a cell-protective ER chaperone protein.
-
ML 145
ML 145 is a selective and potent antagonist of human GPR35, with no significant activity against GPR35 in any of its immediate rodent homologs.
-
Latanoprost acid
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway.
