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Nampt-IN-1
CAS No. 1698878-14-6
Nampt-IN-1( Nampt-IN-1 | Nampt-IN 1 | Nampt-IN1 | LSN3154567 )
Catalog No. M17364 CAS No. 1698878-14-6
Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 80 | In Stock |
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| 2MG | 42 | In Stock |
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| 5MG | 72 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 258 | In Stock |
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| 50MG | 423 | In Stock |
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| 100MG | 625 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNampt-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionNampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
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DescriptionLSN3154567, also known as Nampt-IN-1, is a potent and elective NAMPT inhibitor. Nicotinamide phosphoribosyltransferase (NAMPT) is a promising antitumor target. NAMPT inhibition leads to attenuation of glycolysis, resulting in further perturbation of carbohydrate metabolism in cancer cells.
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In Vitro——
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In Vivo——
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SynonymsNampt-IN-1 | Nampt-IN 1 | Nampt-IN1 | LSN3154567
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PathwayProteasome/Ubiquitin
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TargetCysteine Protease
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RecptorNAMPT|CSF-1R
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1698878-14-6
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Formula Weight419.49
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Molecular FormulaC20H25N3O5S
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 30 mg/mL; 71.52 mM
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SMILESCC(C)(O)CS(=O)(=O)Nc1ccc2CN(CCc2c1)C(=O)COc3cccnc3
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Chemical Name2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhao G, et al. Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration. Mol Cancer Ther. 2017 Dec;16(12):2677-2688.
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