Cart
sales@molnova.com
Desmethyl-VS-5584
CAS No. 1246535-95-4
Desmethyl-VS-5584( Desmethyl-VS-5584 | Desmethyl-VS5584 )
Catalog No. M17217 CAS No. 1246535-95-4
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 91 | In Stock |
|
| 5MG | 145 | In Stock |
|
| 10MG | 257 | In Stock |
|
| 25MG | 430 | In Stock |
|
| 50MG | 621 | In Stock |
|
| 100MG | 883 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDesmethyl-VS-5584
-
NoteResearch use only, not for human use.
-
Brief DescriptionDesmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
-
DescriptionDesmethyl-VS-5584 is a demethyl analogue of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
-
In Vitro——
-
In Vivo——
-
SynonymsDesmethyl-VS-5584 | Desmethyl-VS5584
-
PathwayCell Cycle/DNA Damage
-
TargetPARP
-
RecptormTOR| PI3K
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1246535-95-4
-
Formula Weight340.39
-
Molecular FormulaC16H20N8O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESNc1ncc(c2c3ncn(C(C)C)c3nc(N3CCOCC3)n2)cn1
-
Chemical Name5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Shao Z,et al. VS-5584, a Novel PI3K-mTOR Dual Inhibitor, Inhibits Melanoma Cell Growth In Vitro and In Vivo. PLoS One. 2015 Jul 23;10(7).
molnova catalog
related products
-
BGP-15
A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro.
-
RBN-3143
RBN-3143 is a potent inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM), which inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines, demonstrating research potential for lung inflammation.
-
Rucaparib
An inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.
