c-Kit-IN-1( —— )

Catalog No. M17203 CAS No. 1225278-16-9

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Product Name

c-Kit-IN-1
Note

Research use only, not for human use.
Brief Description

DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
Description

DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).(In Vitro):c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
In Vitro

c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
In Vivo

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Synonyms

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Pathway

Endocrinology/Hormones
Target

CaMK
Recptor

c-Kit| c-Met
Research Area

Cancer
Indication

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1. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1

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