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ST 271
CAS No. 106392-48-7
ST 271( ST-271 | ST271 | ST 271 )
Catalog No. M17133 CAS No. 106392-48-7
ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 5MG | 31 | In Stock |
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| 10MG | 50 | In Stock |
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| 25MG | 90 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | 244 | In Stock |
|
| 200MG | 361 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameST 271
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NoteResearch use only, not for human use.
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Brief DescriptionST271 is an effective protein tyrosine kinase (PTK) inhibitor.
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DescriptionST-271 is tyrphostin tyrosine kinase inhibitor. ST271 reduced intracellular Ca2+ levels and inhibited activation of phospholipase C. Elevation of intracellular Ca2+ regulates agonist-induced activation of phospholipase C and that this contributes to the inhibition of thrombin-induced formation of inositol phosphates by the tyrphostin ST271.
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In VitroST271 partially inhibits peptide phosphorylation in the membrane preparation and in permeabilized platelets. ST271 (100 μM) causes complete inhibition of formation of inositol phosphates induced by FcγRII cross-linking, but also induces a small (< 30%) but significant inhibition of the response to thrombin and U46619.
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In Vivo——
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SynonymsST-271 | ST271 | ST 271
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PathwayOthers
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TargetOther Targets
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RecptorPTK
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Research Area——
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Indication——
Chemical Information
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CAS Number106392-48-7
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Formula Weight272.34
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Molecular FormulaC16H20N2O2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 110 mg/mL 403.91 mM
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SMILESCC(C)c1cc(cc(c1O)C(C)C)/C=C(\C#N)/C(=O)N
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Chemical Name(E)-2-Cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34.
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