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WDR5 WIN site inhibitor C3
CAS No. ——
WDR5 WIN site inhibitor C3( —— )
Catalog No. M17064 CAS No. ——
WDR5 WIN site inhibitor C3 is a potent, specific WIN (WDR5 interaction) site inhibitor of WDR5 with Kd of 1.3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameWDR5 WIN site inhibitor C3
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NoteResearch use only, not for human use.
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Brief DescriptionWDR5 WIN site inhibitor C3 is a potent, specific WIN (WDR5 interaction) site inhibitor of WDR5 with Kd of 1.3 nM.
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DescriptionWDR5 WIN site inhibitor C3 is a potent, specific WIN (WDR5 interaction) site inhibitor of WDR5 with Kd of 1.3 nM; inhibits leukemia cell lines in vitro (MV4:11 cell GI50=6.67 uM), rapidly displace WDR5 from chromatin and decrease the expression of associated genes, causing translational inhibition, nucleolar stress, and p53 induction.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight386.427
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Molecular FormulaC20H23FN4O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3-(((4,5-dihydro-1H-imidazol-2-yl)amino)methyl)-N-(3,5-dimethoxybenzyl)-4-fluorobenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Aho ER, et al. Cell Rep. 2019 Mar 12;26(11):2916-2928.e13.
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