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TDI-2760
CAS No. 956128-08-8
TDI-2760( TDI2760 )
Catalog No. M16824 CAS No. 956128-08-8
TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameTDI-2760
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NoteResearch use only, not for human use.
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Brief DescriptionTDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction.
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DescriptionTDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process; restores the Aβ42-induced decrease in fibrin clot turbidity without affecting normal clotting in an in vitro clotting assay, effectively inhibits Aβ42 fibrillization and modulates Aβ42-induced contact system activation.
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In Vitro——
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In Vivo——
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SynonymsTDI2760
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PathwayOthers
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TargetAmyloids
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RecptorAmyloids
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Research Area——
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Indication——
Chemical Information
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CAS Number956128-08-8
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Formula Weight306.369
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Molecular FormulaC18H18N4O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name5-(3-(dimethylamino)phenoxy)-N-phenylpyrimidin-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Singh PK, et al. Biochemistry. 2018 Feb 27;57(8):1399-1409.
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