Cart
sales@molnova.com
GSK1034702
CAS No. 932373-87-0
GSK1034702( GSK-1034702 | GSK 1034702 )
Catalog No. M16671 CAS No. 932373-87-0
GSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGSK1034702
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5.
-
DescriptionGSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5; improves memory encoding potentially by modulating hippocampal function.Other Indication Phase 1 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsGSK-1034702 | GSK 1034702
-
PathwayGPCR/G Protein
-
TargetmAChR
-
RecptormAChR
-
Research AreaOther Indications
-
IndicationOther Disease
Chemical Information
-
CAS Number932373-87-0
-
Formula Weight333.407
-
Molecular FormulaC18H24FN3O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 2 mg/mL
-
SMILESc1ccc2c(c1)c(nn(c2=O)C[C@H]3CCCN3CCCCc4ccc(cc4)OCCCN5CCCCCC5)Cc6ccc(cc6)Cl
-
Chemical Name7-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Nathan PJ, et al. Int J Neuropsychopharmacol. 2013 May;16(4):721-31.
2. Bradley SJ, et al. Mol Pharmacol. 2018 Jun;93(6):645-656.
molnova catalog
related products
-
AZD6088
AZD6088 (AZD-6088) is a potent and selective, orally bioavailable partial agonist of the M1 muscarinic receptor, reduces heat hyperalgesia in SNL rats with an EC50 of 46.6 nM.
-
Boc-Gly-Gly-Phe-Gly-...
Boc-Gly-Gly-Phe-Gly-OH is a self-assembly of N- and C-protected tetrapeptide.
-
Umeclidinium bromide
Umeclidinium bromide (GSK 573719A) is potent, long-acting, inhaled antagonist of mAChRs with Ki of 0.05-0.16 nM for human M1-M5 mAChRs.
