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KU-60019 (b)
CAS No. 925701-49-1
KU-60019 (b)( KU60019 | KU 60019 | KU-60019. )
Catalog No. M16634 CAS No. 925701-49-1
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 58 | In Stock |
|
| 10MG | 91 | In Stock |
|
| 25MG | 158 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKU-60019 (b)
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NoteResearch use only, not for human use.
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Brief DescriptionKU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays.
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DescriptionKU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR,and is a highly effective radiosensitizer.
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In Vitro——
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In Vivo——
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SynonymsKU60019 | KU 60019 | KU-60019.
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PathwayCell Cycle/DNA Damage
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TargetATM/ATR
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RecptorATM
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Research Area——
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Indication——
Chemical Information
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CAS Number925701-49-1
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Formula Weight547.67
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Molecular FormulaC30H33N3O5S
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Purity>98% (HPLC)
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SolubilityDMSO: 18 mg/mL warmed (32.86 mM)
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SMILESO=C(NC1=CC(CC2=C(C(C3=CC(C=C(N4CCOCC4)O3)=O)=CC=C2)S5)=C5C=C1)CN6C[C@H](C)O[C@H](C)C6
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Chemical Name2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Golding SE, et al. Mol Y Ther, 2009, 8(10), 2894-2902.
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