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RGDS peptide
CAS No. 91037-65-9
RGDS peptide( Arg-Gly-Asp-Ser )
Catalog No. M16537 CAS No. 91037-65-9
RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
|
| 10MG | 48 | In Stock |
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| 25MG | 89 | In Stock |
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| 50MG | 127 | In Stock |
|
| 100MG | 183 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRGDS peptide
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NoteResearch use only, not for human use.
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Brief DescriptionRGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
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DescriptionRGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9; inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor with IC50 of 10 uM.
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In Vitro——
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In Vivo——
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SynonymsArg-Gly-Asp-Ser
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number91037-65-9
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Formula Weight433.417
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Molecular FormulaC15H27N7O8
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 55 mg/mL
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SMILESC(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)N)CN=C(N)N
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Chemical NameL-Serine, L-arginylglycyl-L-α-aspartyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Grigoriou V, et al. J Biol Chem. 2005 Jan 21;280(3):1733-9.
2. Moon C, et al. Respir Res. 2009 Mar 9;10:18.
3. Droppelmann CA, et al. J Biol Chem. 2009 May 15;284(20):13551-61.
4. Gartner TK, et al. J Biol Chem. 1985 Oct 5;260(22):11891-4.
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