FGI-103( FGI103 )

Catalog No. M16519 CAS No. 907169-69-1

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV and MARV.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

FGI-103
Note

Research use only, not for human use.
Brief Description

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV and MARV.
Description

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67); protects mice against a lethal challenge with a mouse-adapted strain of either ZEBOV or MARV-Ravn as a single intraperitoneal dose of 10 mg/kg; reduces viremia and the viral burden in kidney, liver, and spleen tissues in a murine model of ZEBOV infection.
In Vitro

——
In Vivo

——
Synonyms

FGI103
Pathway

Microbiology/Virology
Target

Filovirus
Recptor

Filovirus
Research Area

——
Indication

——

Chemical Information

CAS Number

907169-69-1
Formula Weight

344.369
Molecular Formula

C19H16N6O
Purity

>98% (HPLC)
Solubility

——
SMILES

C1=CC2=C(C=C1C(=N)N)NC(=N2)C=CC3=CC4=C(O3)C=CC(=C4)C(=N)N
Chemical Name

2-[(E)-2-(5-Carbamimidoyl-1-benzofuran-2-yl)vinyl]-1H-benzimidazol-6-carboximidamid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Warren TK, et al. Antimicrob Agents Chemother. 2010 May;54(5):2152-9. 2. Haque A, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):5892-902. 3. De Clercq E. Med Res Rev. 2013 Nov;33(6):1249-77.

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