Cart
sales@molnova.com
WDR5-0103
CAS No. 890190-22-4
WDR5-0103( WD-Repeat Protein 5-0103 )
Catalog No. M16426 CAS No. 890190-22-4
A potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 5MG | 36 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 124 | In Stock |
|
| 50MG | 216 | In Stock |
|
| 100MG | 319 | In Stock |
|
| 200MG | 455 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameWDR5-0103
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay.
-
DescriptionA potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay; inhibits the catalytic activity of MLL1 complex with IC50 value of 5.4 uM.
-
In Vitro——
-
In Vivo——
-
SynonymsWD-Repeat Protein 5-0103
-
PathwayChromatin/Epigenetic
-
TargetHMTase
-
RecptorWDR5
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number890190-22-4
-
Formula Weight383.4409
-
Molecular FormulaC21H25N3O4
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 40 mg/mL
-
SMILESO=C(OC)C1=CC(NC(C2=CC=CC(OC)=C2)=O)=C(N3CCN(C)CC3)C=C1
-
Chemical NameBenzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Li DD, et al. Bioorg Med Chem. 2016 Nov 15;24(22):6109-6118.
molnova catalog
related products
-
UNC3866
A potent, selective PRC1 chromodomains antagonist that binds to CBX4 and CBX7 with Kd of 100 nM.
-
MI-463
MI-463 is a highly potent and orally bioavailable small-molecule inhibitor of menin–MLL.
-
CM-272
CM-272 (CM272)?is a novel potent, selective and reversible dual inhibitor of G9a/DNMTs with IC50 of 8 nM and 382 nM for G9a and DNMT1, respectively.
