Liranaftate

CAS No. 88678-31-3

Liranaftate( Liranaftate | M-732 | Piritetrate )

Catalog No. M16415 CAS No. 88678-31-3

Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 77 In Stock
5MG 48 In Stock
10MG 75 In Stock
25MG 159 In Stock
50MG 284 In Stock
100MG 427 In Stock
200MG 554 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Liranaftate
  • Note
    Research use only, not for human use.
  • Brief Description
    Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.
  • Description
    Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.(In Vitro):Liranaftate showed excellent fungistatic activity against the conidia of T. rubrum. For each of these agents, the MIC after 14 days of contact was 0.009 g/ml. The liranaftate-induced decrease in the MCC occurred from 9 days onwards; MCC at 14 days was 0.039 g/ml . In time-kill studies, liranaftate showed the greatest decrease to a below detection limit in viable counts of T rubrum. The degree of killing of the strain by amorolfine was not greater than that seen by liranaftate, and little reduction of the viable counts by luliconazole and ketoconazole was observed irrespective of concentrations of the agents .
  • In Vitro
    Liranaftate showed excellent fungistatic activity against the conidia of T. rubrum. For each of these agents, the MIC after 14 days of contact was 0.009 g/ml. The liranaftate-induced decrease in the MCC occurred from 9 days onwards; MCC at 14 days was 0.039 g/ml . In time-kill studies, liranaftate showed the greatest decrease to a below detection limit in viable counts of T rubrum. The degree of killing of the strain by amorolfine was not greater than that seen by liranaftate, and little reduction of the viable counts by luliconazole and ketoconazole was observed irrespective of concentrations of the agents .
  • In Vivo
    ——
  • Synonyms
    Liranaftate | M-732 | Piritetrate
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    squalene epoxidase
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    88678-31-3
  • Formula Weight
    328.43
  • Molecular Formula
    C18H20N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: >5mM
  • SMILES
    O=C(OC1=CC=C2CCCCC2=C1)N(SC)C3=NC(OC)=CC=C3
  • Chemical Name
    O-(5,6,7,8,-Tetrahydro-2-naphthyl) 6-methoxy-N-methylthio-2-pyridinecarbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Maruyama N, et al. Med Mycol J. 2012;53(2):129-33.
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