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Home - Products - Cytoskeleton/Cell Adhesion Molecules - Akt - SC-66

SC-66

CAS No. 871361-88-5

SC-66( SC66 | SC 66 )

Catalog No. M16333 CAS No. 871361-88-5

SC66 is an allosteric Akt inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SC-66
  • Note
    Research use only, not for human use.
  • Brief Description
    SC66 is an allosteric Akt inhibitor.
  • Description
    SC66 is an allosteric Akt inhibitor; exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination; has anticancer activity mouse xenograft tumor model.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SC66 | SC 66
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    Akt
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    871361-88-5
  • Formula Weight
    276.3324
  • Molecular Formula
    C18H16N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 34 mg/mL
  • SMILES
    O=C1/C(CCC/C1=C\C2=CC=NC=C2)=C/C3=CC=NC=C3
  • Chemical Name
    Cyclohexanone, 2,6-bis(4-pyridinylmethylene)-, (2E,6E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jo H, et al. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6486-91. 2. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.
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