PKC-IN-7( —— )

Catalog No. M16235 CAS No. 860468-10-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

PKC-IN-7
Note

Research use only, not for human use.
Brief Description

PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM.
Description

PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
In Vitro

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In Vivo

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Synonyms

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Pathway

Angiogenesis
Target

PKC
Recptor

PKC
Research Area

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Indication

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CAS Number

860468-10-6
Formula Weight

443.931
Molecular Formula

C26H22ClN3O2
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

3-(2-chloro-7-((dimethylamino)methyl)naphthalen-1-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786.

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