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WP1066
CAS No. 857064-38-1
WP1066( STAT Inhibitor III )
Catalog No. M16217 CAS No. 857064-38-1
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 5MG | 42 | In Stock |
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| 10MG | 70 | In Stock |
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| 25MG | 126 | In Stock |
|
| 50MG | 209 | In Stock |
|
| 100MG | 293 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 714 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameWP1066
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NoteResearch use only, not for human use.
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Brief DescriptionWP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells.
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DescriptionWP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. Phase 1.
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In Vitro——
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In Vivo——
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SynonymsSTAT Inhibitor III
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PathwayAngiogenesis
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TargetJAK
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RecptorJAK2| STAT3
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number857064-38-1
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Formula Weight356.22
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Molecular FormulaC17H14BrN3O
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Purity>98% (HPLC)
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SolubilityDMSO: 71 mg/mL (199.31 mM)
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SMILESO=C(N[C@H](C1=CC=CC=C1)C)/C(C#N)=C/C2=NC(Br)=CC=C2
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Chemical Name(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Verstovsek S, et al. Clin Y Res, 2008, (3), 788-796.
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