Octreotide

Research use only, not for human use.

Octreotide is a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.

Octreotide is a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.

Western Blot Analysis Cell Line:Human hepatoblastoma HepG2 cell line Concentration:10?8mM Incubation Time:6 hours Result:Increased the protein expression levels of phosphorylated?Akt and GSK3β by 140.8% and 12.2%, respectively and the mRNA level of GS also increased.

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GPCR/G Protein

Somatostatin Receptor

Somatostatin Receptor

Inflammation/Immunology

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83150-76-9

1019.24

C49H66N10O10S2

>98% (HPLC)

DMSO: 10 mM

C[C@H]([C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)[C@@H](CC5=CC=CC=C5)N)C(=O)NC(CO)C(C)O)O

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(-20℃)

With Ice Pack

≥ 2 years