Cart
sales@molnova.com
Quinalizarin
CAS No. 81-61-8
Quinalizarin( Quinalizarin | )
Catalog No. M16041 CAS No. 81-61-8
Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameQuinalizarin
-
NoteResearch use only, not for human use.
-
Brief DescriptionQuinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM.
-
DescriptionQuinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM; shows selectivity over DYRK1a, PIMs, HIPK2, MNK1, ERK8 and PKD1; inhibits endogenous CK2 and induces apoptosis more efficiently than Emodin in Jurkat cells; reduces cell viability with emphasis on adenocarcinoma cells harboring EGFR sensitive mutation, suppresses migration, and accelerates apoptosis in different human lung cancer cell lines.
-
In Vitro——
-
In Vivo——
-
SynonymsQuinalizarin |
-
PathwayMetabolic Enzyme/Protease
-
TargetCasein Kinase
-
RecptorCasein Kinase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number81-61-8
-
Formula Weight272.212
-
Molecular FormulaC14H8O6
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=C2C(O)=CC=C1O)C3=CC=C(O)C(O)=C3C2=O
-
Chemical Name1,2,5,8-Tetrahydroxyanthracene-9,10-dione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Cozza G, et al. Biochem J. 2009 Jul 15;421(3):387-95.
2. Zhou Y, et al. Indian J Cancer. 2015 Dec;52 Suppl 2:e119-24.
3. Pan X, et al. Int J Oncol. 2016 Mar;48(3):1073-84.
molnova catalog
related products
-
PF-5006739
A potent, selective casein kinase CK1δ/ε inhibitor with IC50 of 3.9/17.0 nM, respectively.
-
TA-01
A potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively.
-
Casein kinase 1δ-IN-...
Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases.
