Quinalizarin

CAS No. 81-61-8

Quinalizarin( Quinalizarin | )

Catalog No. M16041 CAS No. 81-61-8

Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
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50MG 1782 Get Quote
100MG 2250 Get Quote
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Biological Information

  • Product Name
    Quinalizarin
  • Note
    Research use only, not for human use.
  • Brief Description
    Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM.
  • Description
    Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM; shows selectivity over DYRK1a, PIMs, HIPK2, MNK1, ERK8 and PKD1; inhibits endogenous CK2 and induces apoptosis more efficiently than Emodin in Jurkat cells; reduces cell viability with emphasis on adenocarcinoma cells harboring EGFR sensitive mutation, suppresses migration, and accelerates apoptosis in different human lung cancer cell lines.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Quinalizarin |
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Casein Kinase
  • Recptor
    Casein Kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    81-61-8
  • Formula Weight
    272.212
  • Molecular Formula
    C14H8O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=C2C(O)=CC=C1O)C3=CC=C(O)C(O)=C3C2=O
  • Chemical Name
    1,2,5,8-Tetrahydroxyanthracene-9,10-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cozza G, et al. Biochem J. 2009 Jul 15;421(3):387-95. 2. Zhou Y, et al. Indian J Cancer. 2015 Dec;52 Suppl 2:e119-24. 3. Pan X, et al. Int J Oncol. 2016 Mar;48(3):1073-84.
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