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Bisantrene
CAS No. 78186-34-2
Bisantrene( CL216942 )
Catalog No. M15949 CAS No. 78186-34-2
A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 31 | In Stock |
|
| 10MG | 41 | In Stock |
|
| 25MG | 91 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | 255 | In Stock |
|
| 200MG | 434 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBisantrene
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
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DescriptionA small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
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In Vitro——
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In Vivo——
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SynonymsCL216942
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PathwayCell Cycle/DNA Damage
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TargetDNA Alkylator
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RecptorTopoisomerase|topoisomerases
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number78186-34-2
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Formula Weight398.46368
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Molecular FormulaC22H22N8
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 133.33 mg/mL
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SMILESC1CN=C(N1)NN=CC2=C3C=CC=CC3=C(C4=CC=CC=C42)C=NNC5=NCCN5
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Chemical Name9,10-Anthracenedicarboxaldehyde, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone]
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Citarella RV, et al. Cancer Res. 1982 Feb;42(2):440-4.
2. Von Hoff DD, et al. Cancer Chemother Pharmacol. 1981;6(2):141-4.
3. Von Hoff DD, et al. Cancer Res. 1982 Feb;42(2):440-4.
4. Lown JW, et al. Mol Pharmacol. 1984 Jan;25(1):178-84.
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