ICG-001( —— )

Catalog No. M15944 CAS No. 780757-88-2

ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	74	In Stock
5MG	61	In Stock
10MG	103	In Stock
25MG	207	In Stock
50MG	352	In Stock
100MG	547	In Stock
200MG	Get Quote	In Stock
500MG	1172	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ICG-001
Note

Research use only, not for human use.
Brief Description

ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM.
Description

ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Wnt/Notch/Hedgehog
Target

Wnt/beta/catenin
Recptor

IC50: 3 μM (CBP)
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

780757-88-2
Formula Weight

548.63
Molecular Formula

C??H??N?O?
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

O=C(NCC1=CC=CC=C1)N2CCC(N([C@@]2(CN(C3=O)CC4=C5C=CC=CC5=CC=C4)[H])[C@H]3CC6=CC=C(C=C6)O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Yan D, et al, Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways. J Biol Chem, 2012, 287(11), 8598-8612.

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