Home - Products - Wnt/Notch/Hedgehog - Wnt/beta/catenin - TNIK-IN-7

TNIK-IN-7

CAS No. 1417795-24-4

TNIK-IN-7( —— )

Catalog No. M37080 CAS No. 1417795-24-4

TNIK-IN-7 is a potent and selective Traf2 and Nck interacting kinase (TNIK) inhibitor (IC50: 11 nM) with antitumor activity for studying signaling and proliferation in colorectal cancer cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	231	In Stock
10MG	352	In Stock
25MG	592	In Stock
50MG	801	In Stock
100MG	1032	In Stock
200MG	1376	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

TNIK-IN-7
Note

Research use only, not for human use.
Brief Description

TNIK-IN-7 is a potent and selective Traf2 and Nck interacting kinase (TNIK) inhibitor (IC50: 11 nM) with antitumor activity for studying signaling and proliferation in colorectal cancer cells.
Description

TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Wnt/Notch/Hedgehog
Target

Wnt/beta/catenin
Recptor

Wnt/beta-catenin
Research Area

——
Indication

——

Chemical Information

CAS Number

1417795-24-4
Formula Weight

386.45
Molecular Formula

C23H22N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

N#CC=1C=CC(OC)=C(C1)C=2C=CN=C(C2)NC3=CC=C(C=C3)N4CCOCC4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Phenibut

Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice.
DK419

DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.
JW74

JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).

Sign In Join Free