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ML116
CAS No. 744270-00-6
ML116( ML 116 | ML-116 )
Catalog No. M15840 CAS No. 744270-00-6
A novel selective STAT3 inhibitor with IC50 of 4.2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 102 | In Stock |
|
| 5MG | 102 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 256 | In Stock |
|
| 50MG | 352 | In Stock |
|
| 100MG | 475 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML116
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NoteResearch use only, not for human use.
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Brief DescriptionA novel selective STAT3 inhibitor with IC50 of 4.2 uM.
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DescriptionA novel selective STAT3 inhibitor with IC50 of 4.2 uM, does not inhibit STAT1, STAT5, or NFkB signaling pathways (IC50>50 uM); inhibits transcription of the STAT3-regulated gene BCL3, sslectively induces loss of viability of breast cancer cell lines such as MDA-MB-468 cells.
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In Vitro——
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In Vivo——
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SynonymsML 116 | ML-116
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number744270-00-6
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Formula Weight309.431
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Molecular FormulaC18H19N3S
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CN(CCC1CC2=CC=CC=C2)C3=C4C=CSC4=NC=N3
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Chemical Name4-benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Assi HH, et al. J Pharmacol Exp Ther. 2014 Jun;349(3):458-69.
2. Madoux F, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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