Cart
sales@molnova.com
Home - Products - JAK/STAT Signaling - STAT - ML116

ML116

CAS No. 744270-00-6

ML116( ML 116 | ML-116 )

Catalog No. M15840 CAS No. 744270-00-6

A novel selective STAT3 inhibitor with IC50 of 4.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 102 In Stock
5MG 102 In Stock
10MG 155 In Stock
25MG 256 In Stock
50MG 352 In Stock
100MG 475 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    ML116
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel selective STAT3 inhibitor with IC50 of 4.2 uM.
  • Description
    A novel selective STAT3 inhibitor with IC50 of 4.2 uM, does not inhibit STAT1, STAT5, or NFkB signaling pathways (IC50>50 uM); inhibits transcription of the STAT3-regulated gene BCL3, sslectively induces loss of viability of breast cancer cell lines such as MDA-MB-468 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ML 116 | ML-116
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    744270-00-6
  • Formula Weight
    309.431
  • Molecular Formula
    C18H19N3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1CN(CCC1CC2=CC=CC=C2)C3=C4C=CSC4=NC=N3
  • Chemical Name
    4-benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Assi HH, et al. J Pharmacol Exp Ther. 2014 Jun;349(3):458-69. 2. Madoux F, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Hispidol

    Hispidol ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.

  • Artesunate

    Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.

  • S3I-201

    S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.

Sign In Join Free