Cordycepin

CAS No. 73-03-0

Cordycepin( 3'-Deoxyadenosine | NSC 63984 | NSC 401022 )

Catalog No. M15794 CAS No. 73-03-0

Cordycepin is a potent inhibitor of IL-1β-induced chemokine production and MMP expression and strongly blocks the p38/JNK/AP-1 signalling pathway in RASFs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 38 In Stock
10MG 33 In Stock
25MG 76 In Stock
50MG 118 In Stock
100MG 179 In Stock
200MG Get Quote In Stock
500MG 449 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cordycepin
  • Note
    Research use only, not for human use.
  • Brief Description
    Cordycepin is a potent inhibitor of IL-1β-induced chemokine production and MMP expression and strongly blocks the p38/JNK/AP-1 signalling pathway in RASFs.
  • Description
    Cordycepin is a potent inhibitor of IL-1β-induced chemokine production and MMP expression and strongly blocks the p38/JNK/AP-1 signalling pathway in RASFs. The effect of Cordycepin on cellular toxicity of RASFs is assessed using MTT assay. Treatment of RASFs with Cordycepin (50 μM or 100 μM) for 24 h does not cause any significant change in cell viability. However, cell viability is slightly decreased when cells are incubated with 100 μM Cordycepin for 48 h.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    3'-Deoxyadenosine | NSC 63984 | NSC 401022
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    TNF-α
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    73-03-0
  • Formula Weight
    251.24
  • Molecular Formula
    C10H13N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: Soluble
  • SMILES
    O[C@H]1[C@H](N2C=NC3=C(N)N=CN=C23)O[C@H](CO)C1
  • Chemical Name
    (2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Noh EM, et al. Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology (Oxford). 2009 Jan;48(1):45-8.
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