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XF-73

CAS No. 718638-68-7

XF-73( Exeporfinium chloride )

Catalog No. M15749 CAS No. 718638-68-7

XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    XF-73
  • Note
    Research use only, not for human use.
  • Brief Description
    XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL).
  • Description
    XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus; inhibits DNA, RNA and protein synthesis and is rapidly bactericidal against S. aureus SH1000, exhibits rapid membrane-perturbing activity.Bacterial Infection Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Exeporfinium chloride
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    718638-68-7
  • Formula Weight
    765.824
  • Molecular Formula
    C44H50Cl2N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[N+](C)(C)CCCOC(C=C1)=CC=C1/C2=C(N/3)\C=CC3=C\C4=N/C(C=C4)=C(C5=CC=C(OCCC[N+](C)(C)C)C=C5)\C(N6)=CC=C6/C=C7C=CC2=N/7.[Cl-].[Cl-]
  • Chemical Name
    1-Propanaminium, 3,3'-[21H,23H-porphine-5,15-diylbis(4,1-phenyleneoxy)]bis[N,N,N-trimethyl-, dichloride (9CI)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ooi N, et al. J Antimicrob Chemother. 2009 Oct;64(4):735-40. 2. Ooi N, et al. J Antimicrob Chemother. 2010 Jan;65(1):72-8. 3. Farrell DJ, et al. Int J Antimicrob Agents. 2010 Jun;35(6):531-6. 4. Farrell DJ, et al. Antimicrob Agents Chemother. 2011 Mar;55(3):1177-81.
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