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Delamanid

CAS No. 681492-22-8

Delamanid( OPC67683 | OPC-67683 | OPC 67683 )

Catalog No. M15601 CAS No. 681492-22-8

A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 44 In Stock
5MG 37 In Stock
10MG 61 In Stock
25MG 120 In Stock
50MG 209 In Stock
100MG 339 In Stock
200MG Get Quote In Stock
500MG 795 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Delamanid
  • Note
    Research use only, not for human use.
  • Brief Description
    A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis.
  • Description
    A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB; shows MIC of 0.006-0.024 ug/mL in vitro and highly effective therapeutic activity at low doses in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    OPC67683 | OPC-67683 | OPC 67683
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antifection
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    681492-22-8
  • Formula Weight
    534.4844
  • Molecular Formula
    C25H25F3N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 30 mg/mL
  • SMILES
    FC(F)(F)OC1=CC=C(OC2CCN(C3=CC=C(OC[C@@]4(C)CN5C(O4)=NC([N+]([O-])=O)=C5)C=C3)CC2)C=C1
  • Chemical Name
    Imidazo[2,1-b]oxazole, 2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-, (2R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Matsumoto M, et al. PLoS Med. 2006 Nov;3(11):e466. 2. Li X, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2256-62. 3. Hurdle JG, et al. J Antimicrob Chemother. 2008 Nov;62(5):1037-45.
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