Veratridine( —— )

Catalog No. M15737 CAS No. 71-62-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Veratridine
Note

Research use only, not for human use.
Brief Description

Veratridine is a benzoate-cevane found in veratrumand Schoenocaulon. It activates sodium channels to stay open longer than normal.
Description

Veratridine is a benzoate-cevane found in veratrumand Schoenocaulon. It activates sodium channels to stay open longer than normal.
In Vitro

Cell Cytotoxicity Assay Cell Line:Neuro-2a cells Concentration:0.25 mM and 1 mM Incubation Time:24 hours Result:Caused around 100% cell mortality (0% cell viability).Cell Viability Assay Cell Line:Cultured mouse DRG neurons Concentration:0.001, 0.1, 1, 10, 30, and 100 μM Incubation Time:Result:Increased responding neurons number from a threshold of 1 μM in a concentration-dependent manner.
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel
Research Area

——
Indication

——

CAS Number

71-62-5
Formula Weight

673.79
Molecular Formula

C36H51NO11
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

C[C@H]1CC[C@H]2[C@@]([C@]3([C@H](C[C@]4([C@@H]5CC[C@H]6[C@]7([C@]5(C[C@]4([C@@H]3CN2C1)O)O[C@@]6([C@H](CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
Chemical Name

——

1.Yoshinaka-Niitsu A, et al. Bioorg Med Chem. 2012 May 1;20(9):2796-802.

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